Custom Peptides
Cayman Chemical 1 2DIbutyryl3PalmItoylrac 10mg
A triacylglycerol; has been found in butterfat and maternal Dufour's glands of Anthophora bees
Cayman Chemical SB 277011AhydrochlorIde 10mg
A selective antagonist of the dopamine D3 receptor (pKi = 8.0); has high oral bioavailability and enters the central nervous system of the rat
Cayman Chemical UR144 N 5chloropentyl na 10mg
Differs from UR-144 by having a chlorine atom on the terminal carbon of the alkyl group; intended for research and forensic applications
Cayman Chemical PasIreotIdeaspartatetrIf 10mg
An SSTR agonist; binds selectively to human SST1, SST2, SST3, and SST5 over SST4 (IC50s = 9.3, 1, 1.5, 0.16, and >100 nM, respectively, for human recombinant receptors); dose-dependently inhibits GHRH-stimulated growth hormone release by primary rat anterior pituitary cells; inhibits ACTH secretion by some primary human corticotrope adenomas (10 nM); inhibits ACTH release and proliferation by mouse AtT20 pituitary corticotrope cells in vitro (10 nM); inhibits tumor growth of subcutaneously implanted AtT20 cells in vivo in nude mice (1.5 μg per day); decreases plasma ACTH concentrations and tumor size in dogs with ACTH-dependent Cushing’s disease (0.03 mg/kg)
Cayman Chemical OxytocInacetate 10mg
A nonapeptide hormone primarily synthesized in the hypothalamus with roles in uterine contraction and lactation, social memory and attachment, sexual and maternal behavior, aggression, learning, anxiety, feeding, and pain perception
Cayman Chemical VU0357017hydrochlorIde 10mg
A selective agonist of M1 mAChRs (Ki = 9.91 µM); selective for M1 over M2-M5 mAChRs (Kis = 21.4-50 µM in CHO cells); increases calcium mobilization and activates the ERK signaling pathway (EC50 = 1.6 and 37 µM, respectively, in CHO cells expressing human recombinant M1 receptors); reverses scopolamine-induced deficits in contextual fear conditioning in rats (10 mg/kg)
Cayman Chemical -CnabIchromen 10mg
An analytical reference standard categorized as a phytocannabinoid; induces catalepsy, hypothermia, hypolocomotion, and antinociception in the mouse tetrad assay for cannabimimetic activity; intended for research and forensic applications
Cayman Chemical L-hydroxy ArgInInacetate 10mg
A substrate for NOS in the formation of NO; as been used as a biomarker for reduced NO formation in patients with cardiovascular disease and metabolic syndrome
Cayman Chemical 20 R-GInsenosIde Rh2 10mg
A steroid glycoside with diverse biological activities; inhibits the replication of MHV-68 (IC50 = 2.77 μM) and the lytic replication of human gammaherpes virus in BC3 cells; reduces levels of NO, PGE2, ROS, and pro-MMP-9 in LPS-stimulated RAW 264.7 cells; reduces ROS production and MMP-9 and MMP-2 activity in HaCat human keratinocytes; induces tumor cell apoptosis and reduces tumor growth in an H22 hepatocellular carcinoma mouse xenograft model at 4 mg/kg
Cayman Chemical ADL5859hydrochlorIde 10mg
A δ-opioid receptor agonist (Ki = 0.84 nM); selective for δ-opioid receptors over μ-opioid and κ-opioid receptors at 10 μM; completely reverses CFA-induced mechanical hyperalgesia in rats at 3 mg/kg; decreases immobility time in the forced swim test in rats
Cayman Chemical ReparIxInL-LysIn salt 10mg
A non-competitive allosteric inhibitor of IL-8/CXCL8 activation of CXCR1 and CXCR2 chemokine receptors (IC50s = 1 and 100 nM, respectively); blocks IL-8-induced leukocyte recruitment (IC50 = 1 nM) and other inflammatory responses, without affecting receptor activation induced by other CXCR1 and CXCR2 agonists; at 100 nM, depletes a cancer stem cell population in human breast cancer cell lines in vitro
Cayman Chemical 3EthylmethcathInonhydroch 10mg
A potential stimulant/entactogen designer drug of the amphetamine, phenethylamine, and cathinone chemical classes; intended for forensic purposes